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Fig. 4 | Journal for ImmunoTherapy of Cancer

Fig. 4

From: B cell depletion or absence does not impede anti-tumor activity of PD-1 inhibitors

Fig. 4

B cell deficiency does not impair anti-tumor immune responses in murine models of colon cancer (MC38) and melanoma (YUMMER1.7). a Survival of mice after implantation of 1 × 105 YUMMER1.7 cells. C57BL/6 J (B6) (n = 8) vs muMT log-rank p = 0.7319 (n = 10). muMT vs Rag1−/− (n = 8) p < 0.0001. b Survival of MC38 tumor bearing mice treated with anti-PD-1. C57BL/6 J vs muMT p = 0.1435, n = 8

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