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Fig. 2 | Journal for ImmunoTherapy of Cancer

Fig. 2

From: DNA damage repair gene mutations and their association with tumor immune regulatory gene expression in muscle invasive bladder cancer subtypes

Fig. 2

MIUC subtypes exhibit distinct expression patterns of immunoregulatory genes. Average z-score of each immune-regulatory gene was obtained per subtype (row). Unsupervised clustering show clustering of basal squamous and luminal infiltrated tumors with higher scores for immunostimulatory genes. Basal squamous showed high expression scores of immunoinhibitors, such as CTLA4, IDO1, TIGIT, LAG3, PD-1, and PD-L1 compared with other subtypes

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