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Table 1 Patient and tumor characteristics

From: Prognostic impact of immune gene expression signature and tumor infiltrating immune cells in localized clear cell renal cell carcinoma

Characteristic

UAB discovery dataset

Fox chase validation dataset

Number (N = 159), %

Recurrers (N = 33), %

Number (N = 198), %

Recurrers (N = 53), %

Median Age

58

59

61

59

Gender

 Female

60 (37.8)

11 (33.3)

55 (27.7)

13 (24.5)

 Male

99 (62.2)

22 (66.7)

143 (72.2)

40 (75.4)

Race

 Caucasian

124 (77.9)

30 (90.9)

190 (96)

51 (96.2)

 AA

19 (12.0)

2 (6)

6 (3.0)

2 (3.7)

 Other

16 (10.1)

1 (3)

2 (1)

0 (0)

Median Follow-up

48.3 mo (24.5–120.5)

56 mo (25.5–119.7)

70.92 (15.4–126.9)

61.9 mo (16.2–126.9)

Median time to recurrence

 

25.8 mo (4.2–114.7)

 

18.4 mo (2.3–85.3)

Pathologic T stage

T1 / T2 / T3/ T4

62 / 20 / 77 / 0(38.9 / 12.6 / 48.5)

4 / 6 / 23 / 0 (12.1 / 18.1 / 69.7)

89 / 31 / 76 / 2 (45 / 15.6 / 38.3 / 1)

17 / 6 / 28 / 2 (32 / 11.3 / 52.8 / 3.7)

Grade

 1–2

43 (27)

6 (18.1)

58 (29.2)

9 (16.9)

 3–4

116 (73)

27 (81.8)

140 (70.7)

44 (83)

Necrosis

 Yes

48 (30.2)

18 (54.5)

61 (30.8)

28 (52.8)

 No

111 (69.8)

15 (45.4)

137 (69.1)

25 (47.1)

Lymphocyte infiltration scoring

 0

10 (6.2)

0 (0)

27 (13.6)

5 (9.4)

 1

56 (35.2)

7 (21.2)

44 (22.2)

10 (18.9)

 2

30 (18.8)

9 (27.2)

48 (24.2)

9 (17)

 3

33 (20.7)

7 (21.2)

31 (15.6)

10 (18.9)

 4

30 (18.8)

10 (30.3)

48 (24.2)

19 (35.8)