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Table 3 Univariate analysis for association of baseline variables with objective tumor recurrence

From: Prognostic impact of immune gene expression signature and tumor infiltrating immune cells in localized clear cell renal cell carcinoma

Characteristic UAB discovery dataset FCCC validation dataset
Odds ratio 95% CI Overall P value Odds ratio 95% CI Overall P value
Pathologic stage: Stage> 1 vs 1 6.11 1.5–24.6 0.0015 2.62 1.3–5.3 0.003
Necrosis: Yes vs No 3.8 1.7–8.5 0.001 3.5 1.7–7.2 0.0002
Grade: High (3, 4) vs Low (1, 2) 8.2 2.1–32.2 0.0052 2.48 1.1–6.3 0.02
Lymphocytes/plasma cells: High (2–4) vs Low (0,1) 3.08 1.19–9.06 0.015 1.59 0.77–3.14 0.24
Lymphocytes/plasma cells: High (3, 4) vs Low (0,1, 2) 1.99 0.85–4.72 0.11 2.29 1.15–4.58 0.014