Fig. 6

in vitro generated TAM secrete growth factors that support the growth and survival of tumor cells. In vitro generated TAM secrete inflammatory cytokines. Culture supernatants were harvested from M1 and M2-like macrophages and in vitro generated TAM conditioned from MDA-MB 231, SK- BR-3, and LK 46 tumor-conditioned media. Data are presented as a heat map for expression of soluble factors in supernatants from each macrophage phenotype