|
Serum LDH levels
|
Normal (0)
|
Increased (+ 1)
|
|
Stage
|
III/IV (0)
|
V (+ 1)
|
|
Substage
|
b (0)
|
a (+ 1)
|
|
Steroids before referral
|
Yes (0)
|
No (+ 1)
|
|
Dogs with diffuse large B-cell lymphoma
|
|
Score
|
Median LSS
|
1-year SR
|
2-year SR
|
3-year SR
|
|
CH
|
CH-IM
|
P
|
CH
|
CH-IM
|
CH
|
CH-IM
|
CH
|
CH-IM
|
|
4 (n = 27)
|
85
|
480
|
< 0.001*
|
0%
|
57%
|
0%
|
15%
|
0%
|
0%
|
|
2–3 (n = 99)
|
190
|
435
|
0.030*
|
23%
|
50%
|
12%
|
18%
|
8%
|
11%
|
|
0–1 (n = 22)
|
286
|
374
|
0.573
|
40%
|
45%
|
40%
|
27%
|
25%
|
11%
|
|
All cases (n = 148)
|
165
|
413
|
0.001*
|
20%
|
51%
|
13%
|
19%
|
8%
|
10%
|
|
Dogs with marginal zone lymphoma
|
|
Score
|
Median LSS
|
1-year SR
|
2-year SR
|
3-year SR
|
|
CH
|
CH-IM
|
P
|
CH
|
CH-IM
|
CH
|
CH-IM
|
CH
|
CH-IM
|
|
3–4 (n = 29)
|
160
|
680
|
< 0.001*
|
9%
|
77%
|
0%
|
36%
|
0%
|
12%
|
|
0–2 (n = 20)
|
560
|
172
|
0.165
|
56%
|
14%
|
38%
|
14%
|
25%
|
0%
|
|
All cases (n = 49)
|
254
|
399
|
0.245
|
30%
|
55%
|
16%
|
28%
|
10%
|
10%
|
- Abbreviations: LDH, lactate dehydrogenase; LSS, lymphoma specific survival; SR, survival rate; CH, chemotherapy; CH-IM, chemo-immunotherapy
- * Significant
