Fig. 4

Persistence and durability of the CD8 T cell responses to 12MP. Persistence of the T cell responses to 12MP are shown in a (ex vivo) and b (IVS) as the number of PBMC dates in which a response was detected (after week 0). The maximum possible is 6 (after baseline). Durability of the T cell response for 3 months after the last vaccine is shown as the proportion of patients with 90% confidence interval (CI) with response detected at d183 (of those evaluated ex vivo (c) and after IVS (d). Also for group 23 (pICLC, V6), the measured immune response magnitudes are shown through week 26 ex vivo (e) and IVS (f)