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Fig. 2 | Journal for ImmunoTherapy of Cancer

Fig. 2

From: Tumor-associated macrophage expression of interferon regulatory Factor-8 (IRF8) is a predictor of progression and patient survival in renal cell carcinoma

Fig. 2

Higher intratumoral IRF8 protein levels are associated with early stage renal cell carcinoma and prolonged survival. a Representative primary RCC cases showing different levels of IRF8 protein expression (upper image IRF8lo, lower image IRF8hi). (b) IRF8 protein expression plotted by clinical stage (T). *P < 0.05 (Kruskal-Wallis test). Data for progression-free survival and overall survival are shown according to stratification based on IRF8 status within primary tumors of RCC patients (panels c and d, respectively). RCC patients with high levels of intratumoral IRF8 (≥ 2 score) had significantly prolonged overall survival than patients with low levels of IRF8 (< 2) based on log-rank test

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