Fig. 1
From: Optimized fractionated radiotherapy with anti-PD-L1 and anti-TIGIT: a promising new combination
Effect of fractionation of RT on CT26 tumors grafted onto immunodepressed (a, b) or immunocompetent (c, d) mice. Growth of irradiated tumors in immunodeficient BALB/C nude mice (a) (n = 6 mice per group) or immunocompetent BALB/C mice (c) (n = 10–12 mice per group) treated with: 0Gy (black), 1×16.4Gy (red), 3x8Gy (blue), 18x2Gy (purple). The averages are expressed ± SEM The average time for the tumor volume to reach 1500 mm3 in each group is shown for immunodepressed mice (b) or immunocompetent mice (d). Not significant (NS); *p < 0.05; **p < 0.01. Non-parametric Mann-Whitney test was used