Fig. 7From: Oncolytic Maraba virus armed with tumor antigen boosts vaccine priming and reveals diverse therapeutic response patterns when combined with checkpoint blockade in ovarian cancerMRI reveals improved tumor control and distinct response patterns following antigen-targeted prime/boost vaccination + anti-PD-1. a Axial T2-weighted images of a mouse over time demonstrating onset and growth of tumor lesions (yellow arrows) following IE9-mp1 tumor implantation (n = 5). b Schematic representation of study design for serial monitoring of response to combination therapy c MR-based tumor volume measurements of peritoneal lesions in mice from control and treatment groups at different times post vaccination (n = 3–5). d Axial T2-weighted images of a representative animal from all 4 experimental groups illustrating differences in tumor growth kinetics. Tumor lesions indicated with yellow arrows. e Temporal changes in the tumor volume of individual animals (n = 9) treated with MIS Vax + MRB-OVA + anti-PD-1 illustrating the heterogeneity in response pattern. Data presented as mean ± SEMBack to article page