From: Immunogenicity of pembrolizumab in patients with advanced tumors
ADA-negative patients | ADA-positive patients, n = 57 | Total patients | ||||
---|---|---|---|---|---|---|
Non-TE NAb negative | Non-TE NAb positive | TE NAb negative | TE NAb positive | |||
Patients in population | 1943 | 19 | 2 | 27 | 9 | 2000 |
Patients with drug-relateda AE, n (%) | 1338 (68.9) | 11 (57.9) | 2 (100) | 21 (77.8) | 6 (66.7) | 1378 (68.9) |
Patients with infusion-related reaction,b n (%) | 43 (2.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 43 (2.2) |