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Fig. 6 | Journal for ImmunoTherapy of Cancer

Fig. 6

From: Molecular and metabolic pathways mediating curative treatment of a non-Hodgkin B cell lymphoma by Sindbis viral vectors and anti-4-1BB monoclonal antibody

Fig. 6

Sindbis virus plus α4-1BB synergistically enhanced T cell glycolysis and oxidative phosphorylation. a GSEA enrichment plot of KEGG (SV + α4-1BB vs. untreated) glycolysis pathway. b The canonical pathways of SV plus α4-1BB Ab stimulation are clustered by IPA. Red square, oxidative phosphorylation. c Both oxygen consumption rate (oxidative phosphorylation) and Extracellular Acidification Rate (glycolysis) were measured by seahorse XFe24. All groups are as indicated (n = 4)

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