Table 2 Adverse events (AEs)
| Â | Step 1 | Step 2 |
|---|---|---|
(n = 22) | (n = 15) | |
AEs, any grades | 21 (95.5) | 15 (100) |
AEs, grade ≥ 3 | 5 (22.7) | 8 (53.3) |
Drug-related AEs, any grades | 14 (63.6) | 10 (66.7) |
Drug-related AEs, grade ≥ 3 | 2 (9.1) | 1 (6.7) |
 Syncope | 1 (4.5) | 0 (0.0) |
 Anemia | 1 (4.5) | 0 (0.0) |
 White blood cell count decreased | 1 (4.5) | 0 (0.0) |
 Lymphocyte count decreased | 0 (0.0) | 1 (6.7) |
 Neutrophil count decreased | 1 (4.5) | 0 (0.0) |
 Platelet count decreaseda | 1 (4.5) | 0 (0.0) |
Infusion-related reactionb,c | 13 (59.1) | 6 (40.0) |
 Chills | 9 (40.9) | 3 (20.0) |
  Grade 1 | 5 (22.7) | 3 (20.0) |
  Grade 2 | 4 (18.2) | 0 (0.0) |
 Pyrexia | 5 (22.7) | 4 (26.7) |
  Grade 1 | 4 (18.2) | 4 (26.7) |
  Grade 2 | 1 (4.5) | 0 (0.0) |
 Hypotension | 5 (22.7) | 2 (13.3) |
  Grade 1 | 2 (9.1) | 2 (13.3) |
  Grade 2 | 3 (13.6) | 0 (0.0) |
 Hypoxia | 4 (18.2) | 1 (6.7) |
  Grade 1 | 1 (4.5) | 0 (0.0) |
  Grade 2 | 3 (13.6) | 1 (6.7) |
 Nausea | 4 (18.2) | 0 (0.0) |
  Grade 1 | 3 (13.6) | 0 (0.0) |
  Grade 2 | 1 (4.5) | 0 (0.0) |