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Table 2 Baseline characteristics

From: A phase I study of the PD-L1 inhibitor, durvalumab, in combination with a PARP inhibitor, olaparib, and a VEGFR1–3 inhibitor, cediranib, in recurrent women’s cancers with biomarker analyses

Characteristics

N = 9

Age, median (range)

59 year-old (44–73)

BRCA mutation status (germline mutation/wild type/unknown)

1/7/1

Tumor type

 OvCa (HGSOC/Clear cell/Mixed Mullerian/ Mixed Serous and Endometrioid)

6 (2/2/1/1)

 Platinum sensitivity in OvCa (sensitive/resistant)

2/5

 Primary Peritoneal cancer (platinum-resistant)

1

 Endometrial carcinoma (MSI low)

1

 Triple Negative Breast Cancer

1

ECOG Performance Status (0/1/2)

3/6/0

Number of previous treatments, median (range)

2 (2–6)

 Prior PARPi (n)

0

 Prior bevacizumab (n)

2

  1. Abbreviations: N number, OvCa ovarian cancer, HGSOC high-grade serous OvCa, MSI microsatellite instability, PARPi poly ADP ribose polymerase inhibitor