Fig. 6From: Development of a new fusion-enhanced oncolytic immunotherapy platform based on herpes simplex virus type 1Effects of combination treatment with Virus 16 and anti-PD1. a-d Individual tumor growth curves of injected (right) and contralateral/un-injected (left) tumors from BALB/C mice bearing A20 lymphoma tumors treated with either (a) vehicle or anti-PD1, b Virus 16 (5 × 106 pfu/dose 3x), or Virus 16 (5 × 106 pfu/dose 3x) and anti-PD1, c Virus 16 (5 × 105 pfu/dose 3x) or Virus 16 (5 × 105 pfu/dose 3x) and anti-PD1 and (d) Virus 16 (5 × 104 pfu/dose 3x) or Virus 16 (5 × 104 pfu/dose 3x) and anti-PD1. Statistical differences between groups were measured by one-way ANOVA with multiple comparisions at day 28. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001Back to article page