Fig. 2

Stable IDO1 overexpression enhances xenograft tumor growth in BALB/c mice. a Average growth curves of subcutaneous xenograft tumors in BALB/c mice after inoculation of CT26 cells with stable IDO1 overexpression (pLenti-IDO1) or with vector control (pLenti-Vector). b Representative pictures of tumors in BALB/c mice from the pLenti-IDO1 group and the pLenti-Vector group. c Tumor weight in mice from the pLenti-IDO1 group and the pLenti-Vector group. d qRT-PCR results and e representative western blots of IDO1 in subcutaneous tumor tissues from the pLenti-IDO1 group and the pLenti-Vector group. # 1 and # 2 represents tumor tissues from different mice. Images are representative of three biological replicates. a Mean ± SEM; c, d mean ± SD. a-d n = 6. a One-way ANOVA and c, d two-tailed Student’s t-test were performed for statistical analysis; **P < 0.01, ***P < 0.001