Table 2 CIK cells therapy-related adverse events according to category and grade
Category | Patients no.(%) | Time to Onset(hours), Median (range) | Time of duration(hour), Median (range) | |||
|---|---|---|---|---|---|---|
Total | Grade 1–2 | Grade 3–4 | treatments | |||
Any | 12(8.0) | 11(7.3) | 1(0.7) | 2(1.3) | 4.5(0.5–30.0) | 12(0.5–36.0) |
Fever | 4(2.7) | 3(2.0) | 1(0.7) | 1(0.7) | 3.75(2.5–6.0) | 6.75(2.0–12.0) |
Chill | 4(2.7) | 4(2.7) | NA | NA | 2.0(1.5–4.5) | 1.25(0.5–2.0) |
Rash | NA | NA | NA | NA | Â | Â |
Pruritus | NA | NA | NA | NA | Â | Â |
Arthralgia/myalgia | 3(2.0) | 3(2.0) | NA | NA | 12.0(8.0–20.0) | 24.0(12.0–36.0) |
Fatigue | 3(2.0) | 3(2.0) | NA | NA | 6.0(4.0–12.0) | 18.0(12.0–24.0) |
Anorexia | 3(2.0) | 3(2.0) | NA | NA | 20.0(6.0–30.0) | 20.0(12.0–36.0) |
Nausea/vomiting | 1(0.7) | 1(0.7) | NA | NA | 1.5(NA) | 12.0(NA) |
Allergic reaction | NA | NA | NA | NA | Â | Â |
Hypertension | 1(0.7) | 1(0.7) | NA | 1(0.7) | 0.5(NA) | 1.5(NA) |
Pneumonitis | NA | NA | NA | NA | Â | Â |
Hepatitis | NA | NA | NA | NA | Â | Â |
Colitis | NA | NA | NA | NA | Â | Â |