Fig. 6

CD8⁺ T cells are necessary for tumor clearance after CPR. Established mEER tumors were treated with CPR and anti-CD8α depleting antibody, or isotype control antibody, according to the schedule in (a); mice were euthanized when tumors reached 225 mm². b CD8⁺ T cell percentages (among CD45⁺ cells) in the blood at day 33 of treatment as assessed by flow cytometry (Dunn’s multiple comparison test; N = 1; n = 8 per group, each as an individual dot). c Individual tumor area by treatment group, with each mouse represented as a single line. d Average tumor area with statistical comparison at time of first control mouse euthanization (Tukey’s multiple comparison test; N = 1 representative of 2; n = 8 per group). e Kaplan Meier survival curves and statistical comparison between treatment groups (Log-rank test; N = 2; n = 12–13). *p < 0.05; ***p < 0.001; ****p < 0.0001