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Table 4 Association between BMI classification change and response/toxicity changes in patients receiving multiple

From: The complex relationship between body mass index and response to immune checkpoint inhibition in metastatic melanoma patients

Change in BMI Classification Higher to lower Constant Lower to Higher P value
N(%) Total = 104 14(13) 86(83) 4(4%)  
Change in ECOG Performance Status Decrease PS 1(7) 3(3) 0(0) 0.41
Constant PS 7(50) 61(71) 3(75)
Increase PS 6(43) 22(26) 1(25)
Change in Number of metastatic sites Decrease # of sites 1(7) 10(12) 2(50) 0.23
Constant # of sites 4(29) 35(41) 1(25)
Increase # of sites 9(64) 41(48) 1(25)
Change in Response Improved OR 5(36) 30(35) 1(25) 0.08
Constant OR 8(57) 24(28) 1(25)
Decrease OR 1(7) 32(37) 2(50)
Change in Toxicity Decrease Toxicity 4(29) 16(19) 3(75) 0.14
Constant Toxicity 5(36) 37(43) 0(0)
Increase Toxicity 5(36) 33(38) 1(25)