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Table 4 Association between BMI classification change and response/toxicity changes in patients receiving multiple

From: The complex relationship between body mass index and response to immune checkpoint inhibition in metastatic melanoma patients

Change in BMI Classification

Higher to lower

Constant

Lower to Higher

P value

N(%)

Total = 104

14(13)

86(83)

4(4%)

 

Change in ECOG Performance Status

Decrease PS

1(7)

3(3)

0(0)

0.41

Constant PS

7(50)

61(71)

3(75)

Increase PS

6(43)

22(26)

1(25)

Change in Number of metastatic sites

Decrease # of sites

1(7)

10(12)

2(50)

0.23

Constant # of sites

4(29)

35(41)

1(25)

Increase # of sites

9(64)

41(48)

1(25)

Change in Response

Improved OR

5(36)

30(35)

1(25)

0.08

Constant OR

8(57)

24(28)

1(25)

Decrease OR

1(7)

32(37)

2(50)

Change in Toxicity

Decrease Toxicity

4(29)

16(19)

3(75)

0.14

Constant Toxicity

5(36)

37(43)

0(0)

Increase Toxicity

5(36)

33(38)

1(25)