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Fig. 7 | Journal for ImmunoTherapy of Cancer

Fig. 7

From: Colorectal cancer cell-derived CCL20 recruits regulatory T cells to promote chemoresistance via FOXO1/CEBPB/NF-κB signaling

Fig. 7

Relationship between the expression of signaling molecules and survival of CRC patients. a Expression of FOXO1, CEBPB, P-P65, and CCL20 in tumor tissues of CRC neoadjuvant chemotherapy patients with chemosensitivity (S) and chemoresistance (R) was detected by immunohistochemistry (100 ×). b IRS of FOXO1, CEBPB, CCL20, and FOXP3 in tumor tissues of CRC neoadjuvant chemotherapy patients (n = 55) analyzed by immunohistochemistry is presented. c Correlations of FOXO1, CEBPB, and RELA with CRC clinical stage were analyzed from TCGA dataset. Z-score defined as the cut-off point. d Kaplan-Meier survival curves for CRC neoadjuvant chemotherapy patients (n = 40) with lower and higher IRS or positive rate of FOXO1, CEBPB, and CCL20 expression (immunohistochemistry analysis). *P < 0.05, **P < 0.01

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