Table 1 TCR genes of CD8+CD137+T cells in pre-stimulated TIL-F1
ID | TRAV | TRAJ | CDR3 aa seq. | TRBV | TRBD | TRBJ | CDR3 aa seq. | CD8+CD137+ | |
|---|---|---|---|---|---|---|---|---|---|
Rank | Freq. (%) | ||||||||
1 | TRAV4*01 | TRAJ8*01 | LVGDGKNTGFQKLV | TRBV7–9*03 | TRBD2*01 | TRBJ2–7*01 | ASSLKPGEQY | 1 | 58.54 |
2 | TRAV1–2*01 | TRAJ40*01 | AVRAPLLPQEPTNT | TRBV7–9*03 | TRBD2*01 | TRBJ2–7*01 | ASSLKPGEQY | 2 | 14.63 |
3 | TRAV1–2*01 | TRAJ16*01 | VPLDGQKLL | TRBV3–1*01 | TRBD1*01 | TRBJ2–5*01 | ASSQESQTGPIGGTQY | 3 | 9.76 |
4 | TRAV13–1*02 | TRAJ52*01 | AASTDNAGGTSYGKLT | TRBV6–6*01 | TRBD2*01 | TRBJ1–2*01 | ASSYGNSGAGGYGYT | 4 | 4.88 |
5 | TRAV8–6*02 | TRAJ32*02 | AVPVVLQTSS | TRBV7–3*01 | TRBD2*01 | TRBJ2–1*01 | ASSLGGNEQF | 5 | 2.44 |
6 | TRAV1–2*01 | TRAJ15*01 | AVRETGQAGTALI | TRBV28*01 | TRBD1*01 | TRBJ2–7*01 | ASRLDRASSYEQY | 6 | 2.44 |
7 | TRAV21*01 | TRAJ6*01 | AAGIRRKLHTY | TRBV19*01 | TRBD1*01 | TRBJ1–1*01 | ASSITGRTEAF | 7 | 2.44 |
8 | TRAV41*01 | TRAJ45*01 | AVSRGHDSGGGADGLT | TRBV6–5*01 | TRBD1*01 | TRBJ2–7*01 | ASSYGDSYEQY | 8 | 2.44 |
9 | TRAV19*01 | TRAJ53*01 | ALSLNSGGSNYKLT | TRBV7–9*03 | TRBD2*01 | TRBJ2–1*01 | ASSPVLNEQF | 9 | 2.44 |