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Table 1 TCR genes of CD8+CD137+T cells in pre-stimulated TIL-F1

From: Isolation of T cell receptor specifically reactive with autologous tumour cells from tumour-infiltrating lymphocytes and construction of T cell receptor engineered T cells for esophageal squamous cell carcinoma

ID TRAV TRAJ CDR3 aa seq. TRBV TRBD TRBJ CDR3 aa seq. CD8+CD137+
Rank Freq. (%)
1 TRAV4*01 TRAJ8*01 LVGDGKNTGFQKLV TRBV7–9*03 TRBD2*01 TRBJ2–7*01 ASSLKPGEQY 1 58.54
2 TRAV1–2*01 TRAJ40*01 AVRAPLLPQEPTNT TRBV7–9*03 TRBD2*01 TRBJ2–7*01 ASSLKPGEQY 2 14.63
3 TRAV1–2*01 TRAJ16*01 VPLDGQKLL TRBV3–1*01 TRBD1*01 TRBJ2–5*01 ASSQESQTGPIGGTQY 3 9.76
4 TRAV13–1*02 TRAJ52*01 AASTDNAGGTSYGKLT TRBV6–6*01 TRBD2*01 TRBJ1–2*01 ASSYGNSGAGGYGYT 4 4.88
5 TRAV8–6*02 TRAJ32*02 AVPVVLQTSS TRBV7–3*01 TRBD2*01 TRBJ2–1*01 ASSLGGNEQF 5 2.44
6 TRAV1–2*01 TRAJ15*01 AVRETGQAGTALI TRBV28*01 TRBD1*01 TRBJ2–7*01 ASRLDRASSYEQY 6 2.44
7 TRAV21*01 TRAJ6*01 AAGIRRKLHTY TRBV19*01 TRBD1*01 TRBJ1–1*01 ASSITGRTEAF 7 2.44
8 TRAV41*01 TRAJ45*01 AVSRGHDSGGGADGLT TRBV6–5*01 TRBD1*01 TRBJ2–7*01 ASSYGDSYEQY 8 2.44
9 TRAV19*01 TRAJ53*01 ALSLNSGGSNYKLT TRBV7–9*03 TRBD2*01 TRBJ2–1*01 ASSPVLNEQF 9 2.44
  1. TCR T-cell receptor, CDR3 Complementarity-determining region, V Variable, D Diversity, J Joining, TRAV T-cell receptor Vα, TRBV T-cell receptor Vβ
  2. *subtypes of TCR genes