Isolation of T cell receptor specifically reactive with autologous tumour cells from tumour-infiltrating lymphocytes and construction of T cell receptor engineered T cells for esophageal squamous cell carcinoma

Table 2 TCR genes of CD8⁺CD137⁺T cells in post-stimulated TIL-F1

ID	TRAV	TRAJ	CDR3 aa seq.	TRBV	TRBD	TRBJ	CDR3 aa seq.	CD8⁺CD137⁺
ID	TRAV	TRAJ	CDR3 aa seq.	TRBV	TRBD	TRBJ	CDR3 aa seq.	Rank	Freq. (%)
1	TRAV4*01	TRAJ8*01	LVGDGKNTGFQKLV	TRBV7–9*03	TRBD2*01	TRBJ2–7*01	ASSLKPGEQY	1	72.09
2	TRAV1–2*01	TRAJ40*01	AVRAPLLPQEPTNT	TRBV7–9*03	TRBD2*01	TRBJ2–7*01	ASSLKPGEQY	2	11.63
10	TRAV13–1*02	TRAJ22*01	APLSGSARQLT	TRBV7–9*03	No Result	TRBJ2–2*01	ASSLVPGELF	3	9.30
11	TRAV8–4*05	TRAJ40*01	VVPTTSGTYKYI	TRBV9*01	TRBD2*02	TRBJ2–3*01	ASSTGGGKTDTQY	4	4.65
12	TRAV39*01	TRAJ42*01	AVEDWGGSQGNLI	TRBV19*01	TRBD2*01	TRBJ2–1*01	ASSPASVGQEQF	5	2.33

TCR T-cell receptor, CDR3 Complementarity-determining region, V Variable, D Diversity, J Joining, TRAV T-cell receptor Vα, TRBV T-cell receptor Vβ
*subtypes of TCR genes