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Table 6 Multivariate Cox regression analysis of overall survival in the study population

From: Impact of antibiotic therapy on the development and response to treatment of immune checkpoint inhibitor-mediated diarrhea and colitis

CharacteristicHR (95% CI)p
ICI type
 Anti-PD-1/PD-L1Reference 
 Anti-CTLA-40.85 (0.56–1.28)0.434
 Combination0.78 (0.58–1.05)0.097
Stage IV cancer1.63 (1.03–2.60)0.038
IMDC0.45 (0.34–0.61)< 0.001
Anaerobic antibiotic therapy1.44 (1.11–1.87)0.007
  1. Abbreviations: HR Hazard ratio, CI Confidence interval