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Fig. 4 | Journal for ImmunoTherapy of Cancer

Fig. 4

From: Clinical and immune profiling for cancer of unknown primary site

Fig. 4

Dot plots for antitumor immune gene expression signatures. CUP cohort (n = 72) was compared with the Prat cohort of ICI-treated solid cancers (n = 63). ad Gene signatures for CD8+ effector T cells, T helper 1 cells, NK cells, and DCs, respectively. e, f Expression of CD274 (PD-L1) and PDCD1 (CD279 or PD-1) genes, respectively. The Prat cohort is divided into PD (n = 29) and non-PD (n = 34) subsets according to the best response to ICI treatment. Each dot represents one patient. The mean and standard error of the mean values are shown for each plot. P values were determined with the Steel-Dwass test for multiple comparisons

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