Skip to main content
Fig. 5 | Journal for ImmunoTherapy of Cancer

Fig. 5

From: Tumor-infiltrating B cells affect the progression of oropharyngeal squamous cell carcinoma via cell-to-cell interactions with CD8+ T cells

Fig. 5

Proportions of dead cells in cultures of bulk and B cell-depleted tumor-derived single cell suspensions. a, b Box plots show the mean proportion of dead CD4+ and CD8+ T cells in bulk (B+) and B cell-depleted (B-) tumor-derived cell suspension after 1 and 6 days of cultivation. c Histograms show differences in the LIVE/DEAD Blue Stain positivity on day 6 in a representative patient. d The heat-map expresses z-scores of relative mRNA expression of indicated genes within Blo (n = 53) and Bhi (n = 52) samples extracted from TCGA databases. e Box plots show the mean expression of indicated genes in tumor tissues and matched PBMCs of Bhi OPSCC patients (n = 4). The boundaries of the box indicate the standard error of the mean and the squares in the box represent the mean. Whiskers indicate the standard deviation. *, p < 0.05; **, p < 0.01 (t test and Mann-Whitney U test)

Back to article page