Fig. 2From: Recovery from secondary adrenal insufficiency in a patient with immune checkpoint inhibitor therapy induced hypophysitisSerum cortisol levels after starting combined immune checkpoint inhibitor therapy. Time 0 is baseline cortisol. Prednisone initiation and discontinuation are indicated by vertical arrows. Serum cortisol values are marked A-J and were drawn at the following times of day – A: 1:30 pm; B: 1 pm; C: 3 pm; D: 2 pm; E: 9 am; F: 1 pm; G: 12:30 pm; H: 12:30 pm; I: 11 am; J: 12 pm. Serum cortisol reference range: 6.7–22.5μg/dLBack to article page