Validation of the predictive function of TET1-MUT. a. Kaplan-Meier curves comparing the overall survival (OS) of patients with TET1-MUT and patients with TET1-WT in the validation cohort. b. Venn diagram showing the concomitant presence of MSI-H and TET1-MUT within patients with known MSI status of the validation cohort. c. Kaplan-Meier curves comparing the OS in the MSI-H, MSI-L/MSS and TET1-MUT, and MSI-L/MSS and TET1-WT groups in the validation cohort. d. Kaplan-Meier curves investigating the prognostic impact of TET1-MUT in the non-ICI-treated cohort from Samstein et al.