| Endocrine AEs in ICIs (6260) | Endocrine AEs in other drugs (233338) |
---|---|---|
Gender | ||
 Male | 3428(54.76) | 106,643(45.70) |
 Female | 2095(33.47) | 95,425(40.90) |
 Missing | 737(11.77) | 31,270(13.40) |
Age | ||
  < 65 | 2481(39.63) | 91,368(39.16) |
  > =65 | 2496(39.87) | 55,099(23.61) |
 Missing | 1283(20.50) | 86,871(37.23) |
Year | ||
 2014 | 116(1.85) | 17,308(7.42) |
 2015 | 59(0.94) | 37,813(16.21) |
 2016 | 944(15.08) | 47,013(20.15) |
 2017 | 1572(25.11) | 62,480(26.78) |
 2018 | 2838 (45.34) | 55,743(23.89) |
 2019Q1 | 731(11.68) | 12,981(5.56) |
Outcome | ||
 Death | 601(9.60) | 9752(4.18) |
 Life-threatening | 474(7.57) | 10,435(4.47) |
 Disability | 108(1.73) | 4958(2.12) |
 Hospitalization | 2329(37.20) | 69,842(29.93) |
 Congenital anomaly | 0(0.00) | 102(0.04) |
 Other serious | 1605(25.64) | 78,742(33.75) |
 Required intervention | 1(0.02) | 50(0.02) |
 Missing | 1142(18.24) | 59,457(25.48) |
Report countries | ||
 United States | 1997(31.90) | 124,384(53.31) |
 Japan | 1748(27.92) | 14,146(6.06) |
 Great Britain | 181(2.89) | 11,376(4.88) |
 France | 393(6.28) | 10,258(4.40) |
 Canada | 62(0.99) | 8741(3.75) |
 Italy | 116(1.85) | 7922(3.40) |
 Other countries | 1033(16.50) | 43,567(18.67) |
 Missing | 730(11.66) | 12,944(5.55) |