Fig. 1From: Metastatic breast cancers have reduced immune cell recruitment but harbor increased macrophages relative to their matched primary tumorsLower immune abundance in metastatic breast tumors (METs) compared to primary breast tumors (PBTs) (a) Total immune score in PBT/MET pairs in Pan-MET dataset, together with the paired changes (MET-PBT). b Paired changes of total immune score removing BRMs in (a). c Total immune score grouped by MET sites. d Stromal tumor infiltrating lymphocytes (sTILs) percentages of 49 pairs of PBT/BRMs in BRM-sTIL dataset. e Spearman’s correlation between sTILs percentages and total immune score for 15 pairs of PBT/BRMs overlapped by Pan-MET and BRM-sTIL. ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05 from two-sided Wilcoxon signed rank test in (a-d) and correlation test in (e)Back to article page