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Fig. 5 | Journal for ImmunoTherapy of Cancer

Fig. 5

From: Systemic and local immunity following adoptive transfer of NY-ESO-1 SPEAR T cells in synovial sarcoma

Fig. 5

Adoptively transferred NY-ESO-1 SPEAR T cells maintain functionality long after infusion. a Representative fields for detection of negative control RNA (DapB), positive control RNA (PPIB, POLR2A), and CD3 or NY-ESO-1c259TCR RNA by RNAish in one patient’s tumor collected over 2 years post-infusion. b A375 target killing shown as green object count as determined by the Incucyte killing assay performed on flow sorted CD3+CD8+dextramer+ T cells (red line) and CD3+CD8+dextramer T cells (grey line) from a patient’s PBMCs collected 12 months post-infusion and on A375 alone (blue line)

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