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Table 1 Patients were treated in four cohorts

From: Systemic and local immunity following adoptive transfer of NY-ESO-1 SPEAR T cells in synovial sarcoma

Cohort

Antigen expression by IHC

Lymphodepletion regimen

1

2+ or 3+ in ≥50% of tumor cells

Flu 30 mg/m2/d × 4 + Cy 1800 mg/m2/d × 2

2

>  1+ in > 1% but < 2+ or 3+ in ≥50% of tumor cells

Flu 30 mg/m2/d × 4 + Cy 1800 mg/m2/d × 2

3

2+ or 3+ in ≥50% of tumor cells

Cy 1800 mg/m2/d × 2

4

2+ or 3+ in ≥50% of tumor cells

Flu 30 mg/m2/d × 3 + Cy 600 mg/m2/d × 3

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