Table 2 Infection Events during the First 30 Days after CART-cell Infusion
Types | CAR19/22 (N = 84) | CAR-BCMA (N = 16) | HSCT + CAR-19/22 (N = 9) | Total (N = 109) |
|---|---|---|---|---|
Any infection† | 14 (16.7) | 3 (18.8) | 2 (22.2) | 19 (17.4) |
Infection grading | ||||
Grade 1–2 | 3 (3.6) | 0 (0.0) | 0 (0.0) | 3 (2.8) |
Grade 3 | 2 (2.4) | 1 (6.3) | 2 (22.2) | 5 (4.6) |
Grade 4–5 | 9 (10.7) | 2 (12.5) | 0 (0.0) | 11 (10.1) |
Infection microorganisms | ||||
Bacteria | 10 (11.9) | 3 (18.8) | 1 (11.1) | 14 (12.8) |
Fungi | 1 (1.2) | 0 (0.0) | 1 (11.1) | 2 (1.8) |
Virus | 3 (3.6) | 0 (0.0) | 0 (0.0) | 3 (2.8) |
Infection site | ||||
Lung | 1 (1.2) | 2 (12.5) | 2 (22.2) | 5 (2.8) |
Bloodstream | 11 (13.1) | 1 (6.3) | 0 (0.0) | 11 (10.1) |
Others | 2 (2.4) | 0 (0.0) | 0 (0.0) | 2 (1.8) |