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Table 2 Infection Events during the First 30 Days after CART-cell Infusion

From: Inflammatory signatures for quick diagnosis of life-threatening infection during the CAR T-cell therapy

Types CAR19/22 (N = 84) CAR-BCMA (N = 16) HSCT + CAR-19/22 (N = 9) Total (N = 109)
Any infection 14 (16.7) 3 (18.8) 2 (22.2) 19 (17.4)
Infection grading
 Grade 1–2 3 (3.6) 0 (0.0) 0 (0.0) 3 (2.8)
 Grade 3 2 (2.4) 1 (6.3) 2 (22.2) 5 (4.6)
 Grade 4–5 9 (10.7) 2 (12.5) 0 (0.0) 11 (10.1)
Infection microorganisms
 Bacteria 10 (11.9) 3 (18.8) 1 (11.1) 14 (12.8)
 Fungi 1 (1.2) 0 (0.0) 1 (11.1) 2 (1.8)
 Virus 3 (3.6) 0 (0.0) 0 (0.0) 3 (2.8)
Infection site
 Lung 1 (1.2) 2 (12.5) 2 (22.2) 5 (2.8)
 Bloodstream 11 (13.1) 1 (6.3) 0 (0.0) 11 (10.1)
 Others 2 (2.4) 0 (0.0) 0 (0.0) 2 (1.8)
  1. Data are presented as number of patients (percentage in each therapeutic group)