Table 2 MS-detected neoantigens
PDO | Source gene | Peptid length (amino acids) | Mutation | WT Peptide | Neoantigen | WT detected | Lowest NetMHC rank (%) WT | Lowest NetMHC rank (%) neoantigen |
|---|---|---|---|---|---|---|---|---|
CRC-01 | U2SURP | 11 | T224R | IQEERDERHKT | IQEERDERHKR | no | 75.8495 | 5.7765 |
CRC-01 | MED25 | 8 | K422 T | SVDANTKL | SVDANTTL | no | 0.5336 | 0.1586 |
CRC-04 | FMO5 | 10 | S423 N | RYVESQRHTI | RYVENQRHTI | no | 0.31911 | 0.2692 |