Blood-derived dendritic cell vaccinations induce immune responses that correlate with clinical outcome in patients with chemo-naive castration-resistant prostate cancer

Table 2 Adverse events

	Vaccinated patients (n = 21)^a
	Grade 1–2	Grade ≥ 3
Reported toxicity (CTCAE 4.0)
Any toxicity	21	0
Anemia	15	0
Flu-like symptoms^b	10	0
Hypoalbuminemia	10	0
Fatigue^c	8	0
Upper respiratory infection	4	0
Dizziness	3	0
Hematoma	3	0
Lymphopenia	3	0
Hypophosphatemia	3	0
Injection site reaction	2	0
Fever	2	0
Headache^d	2	0
AST	2	0
Others^e	1	0

AST aspartate aminotransferase, CTCAE 4.0 Common Terminology Criteria for Adverse Events version 4.0
^aattributed by investigators
^bflu-like symptoms include fever, fatigue, chills, body aches, malaise, loss of appetite and headache
^cfatigue was mentioned separately when it lasted at least 1 day longer than the other flu-like symptoms or when it was present without the other flu-like symptoms
^dheadache was mentioned separately when it was present apart from flu-like symptoms
^eothers include nausea (5%), vomiting (5%), diarrhea (5%), neutropenia (5%), eosinophilia (5%), thrombocytopenia (5%), increased bilirubine (5%) and gamma-glutamyltransferase (5%)