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Table 3 Multivariate Cox regression analysis of clinical parameters and serum biomarkers

From: Combined immune checkpoint blockade for metastatic uveal melanoma: a retrospective, multi-center study

Parameter

Category

HR (95% CI)

P-value

ECOG status

n.a. (ordinal)

3.19 (1.36–7.47)

0.007*

LDH

normal

1

0.428

elevated (>ULN)

1.83 (0.41–8.08)

 

CRP

normal

1

0.534

elevated (>ULN)

1.73 (0.31–9.74)

 

Bone metastasis

no

1

0.331

yes

2.02 (0.49–8.27)

 
  1. Four parameters were included in the multivariate Cox regression analysis. Of these factors, ECOG status was significantly associated with overall survival in this model. Abbreviations: CI Confidence interval, n.a. not applicable, ULN Institutional upper limit of normal, LDH Lactate dehydrogenase, CRP C-reactive protein; *p<0.05.
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