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Fig. 1 | Journal for ImmunoTherapy of Cancer

Fig. 1

From: Radiation myelitis after pembrolizumab administration, with favorable clinical evolution and safe rechallenge: a case report and review of the literature

Fig. 1

The radiological evolution of myelitis. a and b MRI performed at the time of epiduritis diagnosis, sagittal T1-weighted spin-echo and axial fat-suppressed T1 after gadolinium injection show osseous metastasis of L1 with epiduritis (but no enhancement of the spinal cord). c and d MRI after the first signs of myelitis, sagittal and axial fat-suppressed T1 after gadolinium injection show abnormal enhancement of the conus medullaris, and regression of osseous involvement and epiduritis. e MRI at 1 month after the discontinuation of immunotherapy, sagittal T2-weighted spin-echo shows hyperintensity of the conus medullaris. f MRI at 3.5 months, sagittal fat-suppressed T1 after gadolinium injection shows the persistence of conus medullaris enhancement

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