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Fig. 1 | Journal for ImmunoTherapy of Cancer

Fig. 1

From: Sarcosine promotes trafficking of dendritic cells and improves efficacy of anti-tumor dendritic cell vaccines via CXC chemokine family signaling

Fig. 1

Sarcosine concentration and cell phenotype after treating murine BM-DCs with sarcosine. a Mean concentration of intracellular sarcosine. 0.02517pg/cell for control, 0.8274pg/cell for 6mM, 1.14pg/cell for 20mM, 1.145pg/cell for 40mM, 1.145pg/cell for 20mM+EL (0.5mM) and 0.02467pg/cell for 20mM (24hrs) (p<0.0001, ANOVA, n=12 per group). b Flow cytometry of murine BM-DCs to evaluate DC markers CD11c, MHC-II, CD80 and CD86. (BM-DCs collected from 10 mice and experiment was performed in triplicate for each group). BM-DCs=bone marrow derived dendritic cells; DC=dendritic cells; EL=electroporation

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