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Fig. 2 | Journal for ImmunoTherapy of Cancer

Fig. 2

From: PD1Hi CD8+ T cells correlate with exhausted signature and poor clinical outcome in hepatocellular carcinoma

Fig. 2

Phenotypic characteristics of tumor infiltrating PD1Hi CD8+ T cells in HCC. a, A heatmap to show the global phenotypic characteristics of PD1Hi, PD1Int and PD1− CD8+T cells from HCC tumor tissues detected by the flow cytometry. Data represent three individual patients. b-f, Representative flow cytometric overlays of different markers expressed by tumor infiltrating PD1Hi (red line), PD1Int (blue line) and PD1− (black line) CD8+T cells, including co-inhibitory receptors (b), exhaustion associated transcription factors (c), cytotoxic molecules (d), differentiation and activation markers (e-f)

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