Skip to main content
Fig. 3 | Journal for ImmunoTherapy of Cancer

Fig. 3

From: High expression of B7-H3 on stromal cells defines tumor and stromal compartments in epithelial ovarian cancer and is associated with limited immune activation

Fig. 3

Higher tumor-to-stroma ratio (T:S) does not significantly correlate with higher proportions of infiltrating immune cells. A, B, C: Frequencies of T cells (A; n = 24), B cells (B; n = 16), and monocytes (C; n = 18) infiltrating EOC tumors. D: Infiltration scores of tumor-infiltrating CD3+, CD20+, and CD68+ cells in the epithelial or stromal cell compartments. T:S was determined by flow cytometry using B7-H3 staining and is represented below bar graphs by color gradient. Whisker and box plots summarize data from tumors with low (T:S < 1.5; blue) or high (T:S > 1.5; orange) T:S. Statistical significance was determined by Mann Whitney U test

Back to article page