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Fig. 3 | Journal for ImmunoTherapy of Cancer

Fig. 3

From: Combined innate and adaptive immunotherapy overcomes resistance of immunologically cold syngeneic murine neuroblastoma to checkpoint inhibition

Fig. 3

RT and IT-IC does not produce an in situ vaccination effect in immunologically cold 9464D-GD2 neuroblastoma, and response is not improved with immune checkpoint inhibition. Tumor growth curves are shown for intradermal 9464D-GD2 tumors treated with RT alone or RT and IT-IC (a) as well as tumors treated with the addition of checkpoint blockade with anti-CTLA-4 (CTLA) to RT with or without ½ dose IT-IC (b, p values are indicated in Additional file 3: Table S1)

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