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Fig. 1 | Journal for ImmunoTherapy of Cancer

Fig. 1

From: Tumor microenvironment-derived S100A8/A9 is a novel prognostic biomarker for advanced melanoma patients and during immunotherapy with anti-PD-1 antibodies

Fig. 1

S100A8/A9 is expressed exclusively and abundantly in cells of the tumor microenvironment. a Representative image of S100A8/A9 (red staining) and S100B (green staining) antibody co-labelled tissue sections of a metastasized primary melanoma using immunofluorescence. b Representative images of melanoma samples from the tissue microarrays (TMA) stained by immunohistochemistry with a specific S100A8/A9 antibody showing a high proportion of cells with strong S100A8/A9 expression, and showing weak S100A8/A9 staining intensity, respectively. Abbreviations: infl = inflammatory cells of the tumor microenvironment, tu = tumor

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