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Fig. 2 | Journal for ImmunoTherapy of Cancer

Fig. 2

From: Tumor microenvironment-derived S100A8/A9 is a novel prognostic biomarker for advanced melanoma patients and during immunotherapy with anti-PD-1 antibodies

Fig. 2

High numbers of S100A8/A9 positive cells are associated with metastasis of primary melanoma. Dot plot showing the proportion of S100A8/A9 positive myeloid cells in nevi (N = 50), non-metastasizing primary melanomas (NMPMM; N = 41), and metastasizing primary melanomas (MPMM; N = 13) on TMA 1. Black horizontal lines indicate median proportions of S100A8/A9 positive cells. P values were calculated using two-sided Whitney-Mann U test. Abbreviations: MPMM = metastasizing primary melanoma, NMPMM = non-metastasizing primary melanoma, P = P-value, TMA = tissue microarray

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