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Immune monitoring technology primers

Due to advances in cancer immunotherapy, including positive results from clinical trials testing new agents and combinations, emerging new technologies for measuring aspects of immunity, and novel candidate biomarkers from early phase trials, the SITC Immune Biomarkers Task Force has reconvened to review the state of the art, identify current hurdles to further success and to make recommendations to the field.

Reviewed by the members of the SITC Immune Biomarkers Task Force, these brief primers highlight important aspects of both standardized and novel technologies available in clinical trial settings.

Articles

Biomarkers immune monitoring technology primer: Immunoscore® Colon
Fabienne Hermitte
September 2016

Immune monitoring technology primer: whole exome sequencing for neoantigen discovery and precision oncology
Pia Kvistborg, Raphael Clynes, Wenru Song and Jianda Yuan
April 2016

Immune monitoring technology primer: immunoprofiling of antigen-stimulated blood
Laura Rosa Brunet, Samuel LaBrie and Thorsten Hagemann
March 2016

Multiplexed tissue biomarker imaging
Edward C. Stack, Periklis G. Foukas and Peter P. Lee
February 2016

Immune Monitoring Technology Primer: protein microarray (‘seromics’)
Jianda Yuan, Ena Wang and Bernard A. Fox
January 2016

nCounter® PanCancer Immune Profiling Panel (NanoString Technologies, Inc., Seattle, WA)
Alessandra Cesano
December 2015

Quantitative real-time PCR assisted cell counting (qPACC) for epigenetic - based immune cell quantification in blood and tissue
Thomas Oliver Kleen and Jianda Yuan
November 2015

Immune monitoring technology primer: clinical validation for predictive markers
Kevin K. Dobbin
October 2015

Immune monitoring technology primer: flow and mass cytometry
Holden T. Maecker and Alexandre Harari
September 2015

Immune monitoring technology primer: Single Cell Network Profiling (SCNP)
Rachael E. Hawtin and Alessandra Cesano
August 2015

Immune monitoring technology primer: the enzyme-linked immunospot (Elispot) and Fluorospot assay
Sylvia Janetzki
July 2015

Immune monitoring technology primer: immunosequencing
Ilan Kirsch
June 2015

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