https://jitc.biomedcentral.com/articles/10.1186/s40425-015-0074-0
https://jitc.biomedcentral.com/articles/10.1186/s40425-015-0079-8
https://jitc.biomedcentral.com/articles/10.1186/s40425-015-0061-5
https://jitc.biomedcentral.com/articles/10.1186/s40425-015-0077-x