https://jitc.biomedcentral.com/articles/10.1186/s40425-016-0143-z
https://jitc.biomedcentral.com/articles/10.1186/s40425-016-0146-9
https://jitc.biomedcentral.com/articles/10.1186/s40425-016-0145-x
https://jitc.biomedcentral.com/articles/10.1186/s40425-016-0144-y