https://jitc.biomedcentral.com/articles/10.1186/s40425-016-0155-8
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https://jitc.biomedcentral.com/articles/10.1186/s40425-016-0158-5
https://jitc.biomedcentral.com/articles/10.1186/s40425-016-0156-7
https://jitc.biomedcentral.com/articles/10.1186/s40425-016-0160-y